Once you do that, you will need to upload it on your account using the File Manager Tool or via FTP. (Please make sure you upload it in your public_html folder)
Next you need to unpack it by selecting the package and then choosing extract as described on the screenshot.

The files are extracted to a folder named after the version of the PostNuke. You can change the name to the one you want by clicking on the folder and selecting Rename.

Next, please, create a new database from the cPanel – MySQL Databases Area.
Add a username from the cPanel – MySQL Databases Area and add it to the database.
Point your browser to http://yoursite.com/path/to/install.php (if you installed postnuke directly into the www folder on your site, then you would point your browser to http://yoursite.com/install.php
Step 1: Select your language, and then click set language.

Read and accept the General Public License agreement, and click Next.
If the files config.php and config-old.php are set to CHMOD 666 you will see checkmarks indicating this. Click Continue.

! NB: If you do not see the same as the image above, please login to the File Manager tool and set the config.php and config-old.php to 666.
Enter your database information.
Step 4: Setup the Database
Database Host: localhost
Database name: username_database (the name of the database you created. Please note that it gets the user prefix. For example if you add a database called pnuke and your cPanel username is uname the full name of the database is uname_pnuke.
Database username: the username that you created. (Same as the database rules)
Database password: the password for the username.
Table prefix: nuke (it’s a good one for table prefix)
Database type: MySQL
Database Table Type: MyISAM
Leave the rest as it is and click Submit.

Next step confirms the info you have entered. If any of the information is incorrect, click the Change Info button. If the information you have entered is correct, click New Install.
The next page once again confirms the information that you have entered.
At Step 6 a checkbox is there if you wish to create the database. You will not be checking this box, as the database has already been created.

Next page lists all the tables created in your MySQL database. Click the Continue button.
Next, please, enter the information for your Postnuke Admin account. Fill in all the fields, and then click set Login.

You will see a list of updated tables in this step. Click the Finish button.
You have finished your Postnuke Install. Click Go to your PostNuke site to view your newly installed Postnuke tool.